Abstract

Purpose: In this study, we aimed to discuss the laparoscopic cholecystectomy in patients with end stage renal disease compared to the general population. Materials and Methods: We retrospectively evaluated a group of patients with (n = 45) and without (n = 90) end-stage renal disease undergoing laparoscopic cholecystectomy. The groups were compared in terms of length of surgery; duration of hospitalization after surgery; use of blood derivatives; mortality rates; and perioperative, postoperative, and postdischarge complications. Results: Patients with end-stage renal disease exhibited a higher frequency of associated diseases; lower hemoglobin levels; and elevated alkaline phosphatase, blood urea nitrogen, and creatinine values. Statistically significant differences were found between the two groups regarding length of surgery (83.6 ± 14.88 vs. 71.7 ± 11.42 minutes; p p p = 0.011), postoperative (p p = 0.011) rates. Among all patients with end-stage renal disease, 12 (26.7%) were converted to an open procedure (p < 0.001). Conclusion: Despite higher complication rates of laparoscopic cholecystectomy in end-stage renal disease patients, laparoscopic cholecystectomy could be performed safely in patients with end-stage renal disease with low levels of complications and no associated mortality.

Highlights

  • The prevalence of gallstones in patients with end-stage renal disease (ESRD) undergoing dialysis is similar to the prevalence in the general population [1]-[3]

  • We aimed to discuss the laparoscopic cholecystectomy in patients with end stage renal disease compared to the general population

  • From July 2006 to October 2011, 135 consecutive patients who underwent laparoscopic cholecystectomy for symptomatic gallstones were divided into two groups depending on whether they had ESRD or not

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Summary

Introduction

The prevalence of gallstones in patients with end-stage renal disease (ESRD) undergoing dialysis is similar to the prevalence in the general population [1]-[3]. How to cite this paper: Ekici, Y., et al (2014) Outcomes of Laparoscopic Cholecystectomy in Patients with End-Stage Renal Disease. Patients with ESRD receiving hemodialysis are usually immunocompromised and have varying degrees of associated coagulopathy [4]-[7]. The high incidence of concomitant disease in these patients (e.g., diabetes mellitus, liver disease, vascular disease, and amyloidosis) can affect the rates of perioperative and postoperative complications. The main causes of mortality and morbidity in ESRD patients are hemorrhage, infection, and delayed wound healing. There is paucity of knowledge regarding laparoscopic cholecystectomy in ESRD patients

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