Outcomes of Endovenous Cyanoacrylate Closure Using Venaseal ™ System for Chronic Venous Insufficiency

Abstract

Purpose: Endovenous cyanoacrylate closure of saphenous veins is a nonthermal, nonsclerosant ablation technique with satisfactory results. The objective of this study is to indicate the impact of Venaseal™ closure system in chronic venous insufficiency. Methods: Between March 2014- March 2019, 27 patients underwent a total of 40 procedures with the VenaSeal ™ closure system for symptomatic saphenous vein reflux in our hospital. Beside glue ablation procedures, 16 patients underwent concomitant mini phlebectomy, 3 patients underwent perforan vein ligation and 1 patient underwent anterior accessory saphenous vein ligation. The mean age of the patients were 44.4±13.8 (19-67). Doppler ultrasound of the target vein was performed one and 12 months after treatment. Tumescent anesthesia and compression stockings were not used. Results: Mean follow up time was 34.3 ±17 months. The anatomical success rate was 100% at 1 month and 100% at 1 year and there was no recanalization in treated vein segment. All procedures were well tolerated with a median visual analog scale (VAS) pain score of 3.0 (range: 2–5) on a 10-point scale. The mean pre-operative revised venous clinical severity score was 7.5±2.6, which improved to 2.6±0.7, p< 0.001 at one month follow-up. Deep vein thrombosis and pulmonary thromboembolism were not detected. Phlebitis was seen in 2 (7,4%) patients and hypersensitivity reaction occured in one patient (3,7%). Conclusion: Endovenous cyanoacrylate closure of refluxing saphenous veins is a safe and effective method with reduced side effects.