Abstract
For 10 years the authors analyzed 165 clinical cases of children with atopic dermatitis, which manifested in the first year of life. According to the 10-year follow-up, the authors revealed different outcomes of the disease, depending on the severity of the course, clinical forms of dermatitis and the timing of its onset. Favorable outcome with complete remission was observed in 30.9% of cases and was more common in children with a mild course of atopic dermatitis, acute exudative forms and with the onset of the disease at the age over 6 months. The transition to chronic forms was noted in 14.5% of cases and more often took place in children with a moderate severe course of the disease, erythematous-squamous forms and the onset of the disease at the age of 4–6 months. The development of respiratory forms of allergy (allergic rhinitis and bronchial asthma) was noted in 54.6% of cases and was more often detected in patients with a moderate severe and severe atopic dermatitis, erythematous-squamous forms and exudative forms with lichenification and onset of the disease in the first 3 months of life.
Highlights
For 10 years the authors analyzed 165 clinical cases of children with atopic dermatitis, which manifested in the first year of life
Favorable outcome with complete remission was observed in 30.9% of cases and was more common in children with a mild course of atopic dermatitis, acute exudative forms and with the onset of the disease at the age over 6 months
The transition to chronic forms was noted in 14.5% of cases and more often took place in children with a moderate severe course of the disease, erythematous-squamous forms and the onset of the disease at the age of 4–6 months
Summary
Проведен анализ 165 историй развития детей с атопическим дерматитом, начавшимся на первом году жизни, в течение 10 лет. Благоприятный исход с полной ремиссией отмечался в 30,9% случаев и чаще встречался у детей с легким течением атопического дерматита, при острой экссудативной форме и начале заболевания в возрасте старше 6 мес. Развитие респираторных форм аллергии (аллергического ринита и бронхиальной астмы) отмечалось в 54,6% случаев и чаще выявлялось у пациентов со среднетяжелым и тяжелым течением атопического дерматита, эритематозно-сквамозной формой и экссудативной формой с лихенификацией и началом заболевания в первые 3 мес жизни. Цель исследования: изучение различных вариантов исходов атопического дерматита, начавшегося на первом году жизни у детей, в зависимости от тяжести течения, сроков появления и клинических форм заболевания
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