Abstract
Background:Fasting is being used as a therapeutic and cultural practice for millennia. There are numerous reports available on beneficial effects of fasting on various disease conditions. Despite the mounting evidence on fasting, little is known on its physiological effects in humans as most of the studies on physiological effects are done in animals.Methods:Twenty healthy female volunteers (mean age ± SD, 21.95 ± 2.52 years) participated in a 10-day fasting program, which has 1 preparatory day and 1 refeeding day (1,000 kcal) and 8 fasting days (500 kcal). All the participants consented to participate in the study. Blood parameters like complete blood count, renal function test, total iron binding capacity, lipid profile, liver profile, vitamins D and B12, thyroid function tests, glycated hemoglobin, and air blood gas test along with anthropometric measurements were taken on the first and last day.Results:All the parameters under the study have shown statistically significant changes (p < 0.05) except hemoglobin (p = 0.7) and non-high density lipoprotein (p = 0.32). Notable changes were the significant increase in vitamins D and B12 levels that signifies the homoeostatic potential of a fasting regimen.Conclusion:The result depicts the positive impact of fasting on various physiological parameters that warrants further studies on the safety of fasting in diverse diseases, especially the ones that have metabolic disarray as the root cause. Despite the limitation of the smaller sample size and lack of a control group, the results are encouraging to devise disease-specific fasting programs.
Highlights
The patient-centered medical home model stresses the importance of team-based care as a foundation to improving care, costs, and patient experience
New programs like the National Institute for Medical Assistant Advancement38 are creating partnerships between education and practice to enhance training and skills. It is largely incumbent on individual health care organizations to train Medical assistants (MAs) to have a more impactful role in the clinic if they want to deliver on the benefits of team-based care
A multimodal, interdisciplinary, primary carebased, chronic pain clinic equipped with extended appointment times, non-pharmacologic treatment resources, and specialty access can curb opioid usage
Summary
The patient-centered medical home model stresses the importance of team-based care as a foundation to improving care, costs, and patient experience. Emerging evidence indicates that teams can bolster access to care and more effective engagement of practice members in continuous quality improvement (QI).17 Bringing these promising outcomes to fruition requires substantive work for practices that are not organized in this way.. Life expectancy has long been used as a population-based indicator of health as it reflects improvements and changes in public health, health care, economic conditions, and social factors.. The complexity of chronic non-cancer pain in the setting of regulatory efforts to curb opioid usage presents a novel challenge for the medical community Much of this burden falls on primary care clinics. Case presentation: We describe a 66-year-old woman with a significant past medical history of chronic obstructive pulmonary disease and asthma who presented with hypoxia after completing radiotherapy for breast cancer. Despite the mounting evidence on fasting, little is known on its physiological effects in humans as most of the studies on physiological effects are done in animals
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