Abstract

Aim. Takayasu’s arteritis (TA) is a chronic inflammatory disease that affects predominantly the aorta. Percutaneous intervention (PI) may be use the TA. In this manuscript, we studied the outcomes (in-hospital and 6 months later) and effectiveness of PI in patients with TA. Material and methods. The study was performed on 24 consecutive patients (39.3±11.8 (20–61) years; 4 men and 20 women) with TA who were treated with PI, surgical or medical therapy. Nine patients (7 females, 2 male) underwent PI. PI was performed after the erythrocyte sedimentation rate had been normalized in patients with TA. Results. Although 9 patients received PI with stent for subclavian, carotid, renal and coronary artery, 1 patient received PI with only balloon for brachial artery. One percutaneous transluminal angioplasty and 10 stentings were performed. There was not any complication during interventional procedure. The patients were followed for 6 months. After 6 month, the arteries treated were patent and showed no proliferative lesions in Doppler ultrasound at 8 patients. At a woman patient, left subclavian artery restenosis was determined in Doppler ultrasound and confirmed by angiography. During angiography the stenotic lesion has been successfully treated with balloon angioplasty. Conclusions. Takayasu’s patients with active systemic disease must receive immunosuppressive therapy before PI. PI was performed after the active period such as during normal erythrocyte sedimentation rate. In these circumstances, PI in patient with TA may be safely and much less traumatic. Also, recurrence of stenosis in patient with TA has been treated successfully by reintervention without significant complications.

Highlights

  • Takayasu’s arteritis (TA) is a chronic inflammatory disease that affects the large vessels, predominantly the aorta and its main branches and the pulmonary arteries, and it leads to vessel wall thickening, fibrosis, stenosis, and thrombus formation

  • Percutaneous intervention was performed after the erythrocyte sedimentation rate had been normalized (9.80±2.10 mm/h) in these patients

  • Two patients treated before coronary artery bypass surgery and had a left internal mammarian artery (LIMA) bypass graft

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Summary

Introduction

Takayasu’s arteritis (TA) is a chronic inflammatory disease that affects the large vessels, predominantly the aorta and its main branches and the pulmonary arteries, and it leads to vessel wall thickening, fibrosis, stenosis, and thrombus formation. The symptoms of this disease reflect the patient’s high blood pressure and end organ ischemia including coronary, cerebral, and extremity ischemia. Some studies have revealed excellent results of percutaneous intervention for treating patients with TA [3, 4] In this manuscript, we studied the outcomes

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