Outcomes After Surgical Resection of Primary Non-Myxoma Cardiac Tumors.

Kamil Boyacıoğlu,Burçin Çayhan,Arzu Antal Dönmez,Mehmet Altuğ Tunçer,Mehmet Aksüt,Adnan Ak

doi:10.21470/1678-9741-2017-0152

Abstract

ObjectivePrimary cardiac tumors are rare lesions with different histological type. We reviewed our 17 years of experience in the surgical treatment and clinical results of primary non-myxoma cardiac tumors.MethodsBetween July 2000 and February 2017, 21 patients with primary cardiac tumor were surgically treated in our institution. The tumors were categorized as benign non-myxomas and malignants. Data including the demographic characteristics, details of the tumor histology and grading, cardiac medical and surgical history, surgical procedure of the patients were obtained from the hospital database.ResultsEleven patients were diagnosed with benign non-myxoma tumor (male/female:7/4), ranging in age from 10 days to 74 years (mean age 30.9±26.5 years). Papillary ﬁbroelastoma was the most frequent type (63.6%). There were two early deaths in benign group (all were rhabdomyoma), and mortality rate was 18%. The mean follow-up period was 69.3±58.7 months (range, 3 to 178 months). All survivals in benign group were free of tumor-related symptoms and tumor relapses. Ten patients were diagnosed with malignant tumor (sarcoma/lymphoma:8/2, male/female:3/7), ranging in age from 14 years to 73 years (mean age 44.7±18.9 years). Total resection could be done in only three (30%) patients. The mean follow-up period was 18.7±24.8 months (range, 0-78 months). Six patients died in the first 10 months.ConclusionComplete resection of the cardiac tumors, whenever possible, is the main goal of surgery. Surgical resection of benign cardiac tumors is safe, usually curative and provides excellent long-term prognosis. On the contrary, malignant cardiac tumors still remain highly lethal.

Highlights

Cardiac tumors can be categorized as primary or secondary, depending on the origins of the tumors
Ten patients were diagnosed with malignant tumor, ranging in age from 14 years to 73 years
75% of the primary cardiac tumors are benign; the most common histopathological type is myxoma in 50% of the cases, followed by papillary fibroelastomas, fibromas, lipomas, rhabdomyomas, hemangiomas and teratomas[2]

Summary

Introduction

Cardiac tumors can be categorized as primary or secondary, depending on the origins of the tumors. Metastatic malignant heart tumors are nearly 50 times more common than primary cardiac tumors[1]. The presence of primary cardiac tumors is rare with an overall incidence rate of < 0.33%. 75% of the primary cardiac tumors are benign; the most common histopathological type is myxoma in 50% of the cases, followed by papillary fibroelastomas, fibromas, lipomas, rhabdomyomas, hemangiomas and teratomas[2]. Cardiac sarcoma represents the primary malignant tumors of the heart. Lymphoma can affect the heart, primarily[3]. The symptoms of the tumors are non specific and can mimic many other cardiac diseases

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