Abstract
Objectives: The aim of this prospective study was to evaluate the efficacy of fast setting (DentoGen) bonesubstitute for secondary alveolar cleft repair.Materials and Methods: Ten patients with complete unilateral cleft lip and palate were included for alveolarcleft repair with fast setting (DentoGen) without autogenous bone graft in 2017 and 2018. Pre-operation and6 months post-operation CBCT were used for measurement of bone density and bone volume in cleft site.The data was analyzed by using Pearson’s correlation coefficient test and paired sample t-test via SPSSsoftware version 24.Results: The mean age of patients in this study was 10.4±2.657 years. The pre-operative mean alveolar cleftvolume was 0.8996±0.117cm3. Six months after grafting with fast setting (DentoGen) graft, satisfactorybone formation was observed in all patients except two patients. The mean bone density of cleft site was303±42.843 HU which was significantly lower than the non-cleft side, and the mean percentage of new boneformation was 64.74±10.290% compared with original cleft volume.Conclusion: Calcium sulfate hemihydrate (DentoGen) can represent a promising alternative to autogenousbone graft in repairing small unilateral alveolar cleft during mixed dentition.
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