Abstract
Objective: To compare the outcome of four weeks use of High Grade Extract of Chamomile and the placebo on sleep diary data. Study Design: Randomized controlled clinical trial. Place and Duration of Study : Gynecology outdoor, Nishtar Hospital Multan from January 22, 2018 to January 10, 2019. Methodology: Two equal groups were made with 53 menopausal women in each. Age, age at menarche and menopause, and BMI was compared between the two groups. Sleep latency, time and number of awakenings, total sleep time, sleep quality, sleep efficiency, PQSI score, BDI, FSS and STAI-T score were compared between both the groups at baseline and 28 th day. Student t-test was applied using SPSS v.23 computer software. P>0.05 was considered statistically insignificant. Results: After 4 weeks of treatment, significant improvement was observed in sleep latency, time of waking after sleep onset, number of awakenings and total sleep time in the Chamomile group compared with placebo group (0.023, 0.002, 0.019 and <0.001, respectively). The improvement in STAI score was statistically significant (0.024) in the chamomile group. , There was some improvement observed in the chamomile group in terms of sleep quality (0.075) and sleep efficiency (0.059) but the differences were still statistically insignificant. Conclusion: It is concluded that chamomile extract has significant beneficial effects on the menopausal women suffering from sleep disorders. Keywords: menopause, sleep disorders, chamomile extract DOI : 10.7176/JMPB/52-12
Highlights
IntroductionMenopause is term which describes those changes which a women undergoes just before or after the complete cessation of menstruation
Menopause is an age related condition, experienced by all women
When the treatment was continued for at least four weeks and data was recorded again, a significant improvement was observed in sleep latency, time of waking after the onset of sleep, number of awakenings and total sleep time in the Chamomile group when compared with placebo group (p value 0.023, 0.002, 0.019 and
Summary
Menopause is term which describes those changes which a women undergoes just before or after the complete cessation of menstruation This marks the end of reproductive age. In the study by Kupfersztain et al 11 observed that there was a significant alleviation of fatigue and sleep disturbances by twelve weeks use of herbal extract of chamomile. Some studies have been conducted to observe the efficacy of use of chamomile extract in improving the sleep disorders and day time functioning capabilities in general population but the data is still lacking. We steered current study to detect the effectiveness of four weeks use of high quality chamomile extract in removing the complaints of sleep disturbances by the post-menopausal women when compared with the patents who received placebo
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