Abstract

Background: Juxta articular giant cell tumors around the knee constitute 50-60% of the total cases reported. If the disease is detected at an advanced stage, reconstruction of the joint after tumor excision poses problems and has poor functional outcome. The aim of the study was to determine the functional outcome after resection of juxta-articular giant cell tumors around the knee and its reconstruction with mega prosthetic arthroplasty will be analyzed.Methods: Between January 2017 and March 2021, 14 patients in the age group of 28-48 years (mean=42.85 years) with Campanacci stage three giant cell tumors around the knee were studied (12-distal femur patients, 2-proximal tibia). Patients underwent tumor excision and reconstruction with modular megaprosthesis. They were evaluated post-operatively using the Revised Musculoskeletal Tumor Society Score (MSTS) for lower limb. Results: All the patients were followed up for 12-44 months (mean=29.5 months), the average knee flexion at 6 months being 116.4 degrees. The mean MSTS at 6, 12, 18 and 24 months are 19.45, 23.23, 26.61 and 28.77 respectively. Complications observed were infection and tumor recurrence. Conclusions: In advanced cases where tumor excision leaves large bone segment loss, reconstruction with megaprosthesis can give desirable functional outcome.

Highlights

  • Giant cell tumor (GCT) is a benign but locally aggressive neoplasm that constitutes around five percent of all bone tumors.[1]

  • All the patients included in the study were diagnosed with Campanacci stage III GCT around the knee

  • 30 patients presented with juxtaarticular giant cell tumor around the knee, out of which 14 patients were included in the study group after applying exclusion criteria

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Summary

Introduction

Giant cell tumor (GCT) is a benign but locally aggressive neoplasm that constitutes around five percent of all bone tumors.[1]. Malignant transformation is reported in only ten percent of total cases.[4] The primary aim in the management of locally aggressive giant cell tumor is to eradicate it while providing the patient with a stable and functional joint.[2] Enneking's and Campanacci's radiographic classifications are helpful in planning the initial surgical treatment. Those tumors with more active and aggressive lesions have a high rate of recurrence (2050%) when treated with curettage with reconstruction of cavity with bone graft or cement.[5,6] To reduce recurrence rate, wide local excision is done for these tumors. Conclusions: In advanced cases where tumor excision leaves large bone segment loss, reconstruction with megaprosthesis can give desirable functional outcome

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