Abstract
CHD is the most common birth defect in the US. Improved supportive care has resulted in more pediatric and adult survivors who may develop indications for HSCT. We hypothesized there would be overrepresentation of CHD in children undergoing HSCT, as several inherited immune and bone marrow (BM) failure disorders are associated with an increased CHD prevalence. As HSCT outcomes of patients (pts) with CHD are not well known, we conducted a retrospective chart review of 1185 sequential HSCT on 1031 pts performed at Children's Hospital Boston from 1989-2007.
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