Outcome of Follicular Unit Extraction in Cicatricial Alopecia

Abstract

Background: Cicatricial alopecia is a group of disordersthat destroy hair follicles which are replaced with fibrosis,causing permanent hair loss. Cicatricial alopecias are subdividedinto two groups “primary” and “secondary”. For managementof 2ry cases, there are different strategies whichdiffer with the location, size and other scarred area characteristics.These strategies include certain surgical proceduressuch as excision, flap surgery, use of tissue expansion, andhair transplantation that gained popularity as a permanentmethod for restoring hair loss. In cicatricial alopecia cases,hair transplant is considered challenging because of thedegenerative changes and decreased vascularity of these areasthat may produce a lower survival rate of donor hair.Aim of Study: This study aimed to evaluate the role ofPRP and nanofat injections together with follicular unitextraction technique in restoration of hair in secondary cicatricialalopecia.Material and Methods: This study was conducted on 30patients with secondary cicatricial alopecia. Patients weredivided into 3 groups, 10 patients in each. Group A: ReceivedPRP with hair transplantation, group B: Received nanofatinjections with hair transplantation, while in group C (Controlgroup) patients underwent hair transplantation only.Results: Although adding PRP or nanofat injections withhair transplantation procedure provides an excellent improvementin the texture and quality of the scarred tissues comparedto other cases underwent without, there were no significantdifferences in the clinical outcomes of hair restoration includinghair growth density.