Abstract
Current neonatal delivery room (DR) resuscitation teaching includes the use of chest compressions and/or intratracheal epinephrine (CPR) for infants with a heart rate 750 gm birthweight. Methods: We evaluated the outcome of all inborn infants whose birthweights (BW) were 750gm(15/98). Surviving infants were followed up to 36 months adjusted age (AA) using standardized neurodevelopmental (ND) assessments including the Amiel-Tison Neurologic Screen and the Gesell Developmental Screening Inventory. Results: Overall, 21 infants required CPR in the DR, of whom 13 were < 750 gm. Three infants, all < 750 gm, have normal neurodevelopmental outcome at 6, 19,& 26 months AA. These preliminary results indicate that intact survival is possible for infants of < 750 gm BW following CPR in the DR as defined above. Further information is required regarding the indications for CPR, the use of the individual components(compressions and epinephrine) and the duration of CPR from retrospective and prospective evaluation of larger data sets. In addition, we require more complete neurodevelopmental follow-up in order to develop recommendations for the use of CPR in the DR resuscitation of the < 1000 gm birthweight infant. Table
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