Abstract
Introduction: Hematuria (presence of >5 RBCs/HPF) may be a transient outcome or indicator of significant renal disorder in children. Children with neither symptoms of a disease nor a physical abnormality who have microscopic hematuria should be placed in the category of isolated microscopic hematuria (IMH). Objectives: The aim of this study was to evaluate the course of IMH.Patients and Methods: This investigation is an observational study of 124 patients referred to pediatric nephrology clinic from 2002-2012 with IMH. Results: In this study, 124 patients, 40 (32.3%) female and 84 (67.8%) male were evaluated. The mean age was 5.6±2.4 years. The mean follow-up time was 14.3 ± 14.4 months. This mean for 45.2% of the patients, was less than 6 months and for 4% of the patients, it was more than 4 years. The reasons for discovering hematuria were; 66.1% after routine evaluation, 21.8% due to positive family history and 12.1% after urinary tract infection (UTI). In this study, all the laboratory tests and kidney function were normal, except for the presence of microscopic hematuria. Conclusion: It was concluded that IMH without renal failure, hypertension (HTN) and proteinuria is a benign condition with no need for kidney biopsy.
Highlights
Hematuria may be a transient outcome or indicator of significant renal disorder in children
Implication for health policy/practice/research/medical education: We concluded that microscopic isolated hematuria without symptoms of renal failure, HTN and proteinuria is a benign condition with no need for kidney biopsy
When this condition is accompanied by normal renal function and without hypertension (HTN), proteinuria or family history of renal failure, isolated microscopic hematuria (IMH) was applied for patients
Summary
Hematuria (presence of >5 RBCs/HPF) may be a transient outcome or indicator of significant renal disorder in children. The presence of blood or protein in urine may be a transient finding that usually accompanies a nonspecific viral infection It can sometimes be an indicator of glomerular or urinary tract disorder [1,2]. The finding of the study in which children and young adults with persistent asymptomatic isolated microscopic hematuria (IMH) were evaluated is unclear [6], while only a few population based studies have addressed the longterm outcomes of this condition among children. This problem prompted the evaluation of children referred
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