Abstract

This study analyses the relationships between hand strength and function in ambulant and non-ambulant patients with Duchenne muscular dystrophy (DMD) or spinal muscular atrophy (SMA). The maximal handgrip and key pinch strength were measured with the MyoGrip and MyoPinch dynamometers, respectively. Hand function was assessed using the MoviPlate, the Motor Function Measure items for distal upper limb (MFM D3 UL) and the Cochin scale. The data of 91 DMD and 77 SMA patients from 3 natural history studies were analysed (age range 6-31 years).

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