Abstract
The most common type of therapy-resistant epilepsy is temporal lobe epilepsy (TLE). Unilateral TLE usually has a favourable prognosis with resective surgery. However, surgery is usually not considered in cases of bilateral temporal lobe epilepsy (bi-TLE) which occurs in 10–20% of patients with TLE. Vagus nerve stimulation (VNS) is approved as a palliative therapeutic option. The outcome of treating bi-TLE with VNS is unknown. Our study evaluates the effect of VNS on the reduction of seizure frequency in therapy-resistant epilepsy patients with biTLE.
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