Abstract
BackgroundValvular heart disease, including rheumatic heart disease (RHD), is an important cause of heart disease globally. Management of advanced disease can include surgery and other interventions to repair or replace affected valves. This article summarises the methodology of a study that will incorporate enhanced data collection systems to provide additional insights into treatment choice and outcome for advanced valvular disease including that due to RHD.MethodsAn enhanced data collection system will be developed linking an existing Australian cardiac surgery registry to more detailed baseline co-morbidity, medication, echocardiographic and hospital separation data to identify predictors of morbidity and mortality outcome following valve surgery.DiscussionThis project aims to collect and incorporate more detailed information regarding pre and postoperative factors and subsequent morbidity. We will use this to provide additional insights into treatment choice and outcome.
Highlights
Valvular heart disease, including rheumatic heart disease (RHD), is an important cause of heart disease globally
Sample size The sample size will be based on the number required to detect a difference in major adverse prosthesis-related events (MAPE) between bioprosthetic and mechanical valve replacements
The finding that neither prior nor new post-operative AF was found to be an independent predictor of survival in RHD versus non-RHD valve surgery highlights the importance of considering these conditions as separate entities in the setting of valve surgery [28]
Summary
Valvular heart disease, including rheumatic heart disease (RHD), is an important cause of heart disease globally. Management of advanced disease can include surgery and other interventions to repair or replace affected valves. This article summarises the methodology of a study that will incorporate enhanced data collection systems to provide additional insights into treatment choice and outcome for advanced valvular disease including that due to RHD. Valvular heart disease can be congenital or acquired. Management of valvular heart disease can involve a combination of medication, surgical repair or valve replacement with a mechanical or bioprosthetic valve. There were 9,276 heart valve repair or replacement procedures reported in Australia in the year 2013–14 [1]. A particular cause of acquired valvular heart disease is rheumatic heart disease (RHD). Whilst rare in high income countries [2, 3], it remains a condition of global health importance and an important cause of
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