Abstract
These retrospective observational data were collected to understand the role of vasopressin in the hemodynamic management of neonates with shock in a tertiary-level NICU over a period of 2 years. This included 28 neonate who received vasopressin for different clinical states with hypotension like septic shock, MAS with PPHN, Sepsis with PPHN, PPHN with CDH, HOCM, and even in end-organ injury (AKI) with sepsis. The response to vasopressin was 78.5% with improved signs of shock. The overall mortality rate was 15%. This is an attempt to understand vasopressin use in very sick neonates. Randomized controlled trials are required for its use as a treatment protocol.
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