Abstract
Background: Gamma-irradiated sterile cornea (GISC) is a non-immunogenic, cross-linked, sterile patch graft in which the donor keratocytes and endothelial cells are eliminated. It can serve as a graft to cover glaucoma drainage devices, as a graft tissue for frank or impending corneal perforations in tectonic keratoplasty, as a graft tissue in lamellar keratoplasty, and as a carrier tissue for keratoprosthesis. The authors present their experience in treating severe ulcers with microperforations using GISC. Methods: In 2021, eight patients with corneal ulcers unresponsive to medical treatment were chosen to be candidates for VisionGraft® (Corneagen) GISC transplantation and underwent successful corneal surgery. Results: In 6 out of the 8 patients, the patch graft successfully restored tectonic support until optical keratoplasty could be performed if decision was made to improve visual acuity later. The remaining 2 grafts did not epithelialize after surgery and developed sterile corneal melt. Conclusion: This case series supports the use of VisionGraft® GISC as a graft for restoring the anatomy of the eyeball in the setting of corneal perforation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
