Our experience in managing patients with dry eye syndrome

Abstract

Aims: To confirm the effectiveness of a comprehensive approach to the treatment of patients(PT) with moderate and moderate severity of dry eye syndrome (DES).Methods: 53 PT (106 eyes) with 2 and 3 stages of DES aged from 25 to 52 years were included in the examination. The control group (I gr) included 19 PT, in the studied group (II gr)–29 PT. In addition to the standard ophthalmological examination, the PT underwent a Schirmer's test (SCH), Symptomatic Break –Up Time (SBUT), compression test to assess the secretory capacity (Korb, 2005) of the meibomian glands(MG) (using a glass rod) and Ocular Surface Disease Index Questionnaire (OSDI). The TFOS DEWS II report was used to classify the stage of DES. The inclusion criteria: PT with the SCH‐values ≥3 mm, without systemic diseases, the degree of violation of the excretory ability of the MG corresponded to stages 1 and 2. PT of the II gr were offered complex treatment:1‐instillation of drops with hyaluronic acid 5 times a day; 2‐in 2–3 min use of drops with the LIPITECH system; 3– a carbomer‐gel once at night;4‐systematic massages of the eyelids a course of 5–10 sessions over 1.5 months. PT of the I gr continued to use artificial tears min 3 times a day. Control was at 2, 4 and 6 weeks.Results: Positive dynamics are noted in the II gr for all 4 control indicators. The average indicative of SCH increased by 54.7% (7.5 ± 0.04 mm), SBUT improved by 35.6% (3.6 ± 0.01 s), the duration (time from the beginning) of meibum evacuation decreased by 37.7% (2.3 ± 0.08 s); the OSDI decreased by 54.8% (38.0 ± 0.1) (p < 0.05). The I gr: SCH increased by 20.8% (1.5 ± 0.01 mm), SBUT improved by 12.6% (0.9 ± 0.09 s), the duration of meibum evacuation decreased by 5.7% (0.4 ± 0.04 s); the OSDI‐36.2% (24.9 ± 0.7) (p < 0.05).Conclusions: With a comprehensive approach to the problem and the patient's understanding of the need to comply with all recommendations, it is possible to achieve a prolonged positive result of treatment, and to preserve this effect in the future.