Abstract

IntroductionEndoscopic ultrasound guided choledochoduodenostomy (EUS-CDD) with electrocautery enhanced lumen apposing metal stents (EC-LAMS) has emerged as a viable option in the management of patients with malignant distal biliary obstruction (MDBO)....

Highlights

  • Endoscopic ultrasound guided choledochoduodenostomy (EUS-CDD) with electrocautery enhanced lumen apposing metal stents (EC-LAMS) has emerged as a viable option in the management of patients with malignant distal biliary obstruction (MDBO)

  • 91 UGI cancers were diagnosed; with 3 (3%) UGI cancers diagnosed in patients with EDS

  • The factors associated with UGI cancer and selected to develop CDS included: age odds ratio 1.05; male 3.95 (2.36-6.58); progressive dysphagia 2.30 (1.39-3.79); unintentional weight loss 3.28 (2.02-5.31); acid reflux symptoms 0.47 (0.25-0.88) and dysphagia localised to the neck (0.26 (0.12-0.57)

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Summary

Introduction

Endoscopic ultrasound guided choledochoduodenostomy (EUS-CDD) with electrocautery enhanced lumen apposing metal stents (EC-LAMS) has emerged as a viable option in the management of patients with malignant distal biliary obstruction (MDBO). We conducted a multi-centre collaboration from the UK and Ireland with an aim to analyse the pooled efficacy, safety and long term outcomes of EUS-CDD for treatment of MDBO. Due to the mismatch between endoscopy capacity and demand, many centres use in-reach services at weekends. We used data from the National Endoscopy Database to investigate whether (1) patient characteristics on weekdays and weekends differ and (2) weekend procedures are associated with lower polyp detection, after accounting for patient characteristics

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