Ototoxicity in tuberculosis treatment in South Africa: Exploring the current status

Abstract

As a result of the known ototoxic effects of some of the medications used for tuberculosis (TB) treatment, healthcare workers involved in treating TB patients need to be aware of the ototoxic signs and when to refer to an audiologist for hearing monitoring. The main objective of the present paper was to determine the knowledge and management of ototoxicity related to TB treatment by South African healthcare workers. Telephonic interviews using a semi-structured interview schedule consisting of closed- and open-ended questions were conducted on 100 healthcare workers involved in the treatment of patients with TB. Findings were collated and analyzed via thematic analysis and quantitative descriptive statistics procedures. A large percentage of participants were not aware of what ototoxicity is and what the role of the audiologist was in the management of TB patients. All participating public health facilities do not work with an audiologist as a member of the team in the management of TB patients, and a stark lack of ototoxicity monitoring programs exists. Results highlight the need for education of health-care workers as well as patients regarding ototoxicity. Additionally, audiologists need to become more involved in establishing and implementing ototoxicity monitoring programs in facilities where ototoxic medications are prescribed. Key words: Aminoglycosides, ototoxicity, tuberculosis, health care.