Abstract
Ototoxicity is one of the unwanted side effects of a number of medical drugs. Within this category of drugs, aminoglycocides antibiotics and platinum derivates are the most well known. Cis‐platinum and carboxy platinum are often used as anticancer drugs, for example, in cases of testicular and ovarian malignancy. Auditory damage may be reduced by changes in dose, way of administration, and composition of the medical drug treatment. In these cases, early detection of ototoxicity is vital. As ototoxicity appears to be most pronounced in the higher frequencies, it can be assessed at an earlier stage by using high‐frequency audiometry from 8 to 20 kHz. The reference curves in this frequency region are strongly age related. In addition, we have investigated the precision of the measurement. In spite of inaccuracies of headphone positioning, which may influence high‐frequency thresholds above all, standard deviations were obtained as for audiometry in the normal‐frequency range. Finally, some case studies will illustrate the importance of high‐frequency audiometry.
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