Otology/Neurotology

Abstract

Introduction: We assess early hearing preservation (HP) outcomes of patients implanted with the new Slim 20 lateral wall array (CI624);compare early HP outcomes with and without real-time electrocochleography (RT-ECochG);and explain the role of RT-ECochG feedback to improve HP. We believe this abstract is suitable for a late-breaking abstract as we are the first to report early HP outcomes for a new Slim 20 lateral wall electrode (CI624). Since the CI624's release in May 2020, it is becoming increasingly popular among centers as a potential HP array. To our knowledge, there have not been any discussions at major conferences or published studies reviewing experiences with the CI624. Based on our early experience with 29 implantations using this electrode, we have found poor HP outcomes 1 month postoperatively with preservation in only 16 of the recipients. As a result, we began using real-time monitoring of cochlear health during the insertion (ie, electrocochleography [ECochG]) to potentially improve HP outcomes with the CI624. By using real-time ECochG (RT-ECochG) and particularly focusing on minimizing trauma at the end of insertion, we achieved superior early HP rates with this array (8/9 patients, 88.9%). Our preliminary data suggest that full insertion of the CI624 without ECochG results in unpredictable and relatively poor HP outcomes. We suspect that this is related to the CI624 being a longer electrode than previous hybrid arrays resulting in trauma to the apical-most hair cells and neural elements at full insertion. Thus, RT-ECochG may be required for predictable early HP using the CI624. As a result of the COVID-19 pandemic, we were unable to achieve sufficient implantations for submission of an abstract in January 2021. However, we have now performed 9 implants with the CI624 in the past 6 months using RT-ECochG for HP candidates. We believe that our experience with and without ECochG has resulted in an early critical finding that may influence how this implant is used in HP candidates. Methods: A longitudinal study was designed with postlinguistically deafened adults undergoing implantation with CI624 from 2020 to 2021. Pure-tone audiometry preoperatively and 1 month postoperatively were obtained. HP was defined as low-frequency pure-tone average (LFPTA;125, 250, 500 Hz) 5 μV ECochG response drop, array adjustments (ie, withdrawal ∼1 mm, 5° anti-modiolar rotation) were made to facilitate response recovery. Results: A total of 38 implants were performed. There was no scalar translocation on postoperative CT scans and mean apical insertion angle was 338.1° ± 86.4°. Full insertion was performed in most cases;however, partial insertion was performed if the RT-ECochG response dropped during insertion of the final 3 electrodes (n = 4). Of the 29 patients where RT-ECochG was not used, 16 (55.2%) had low-frequency HP postoperatively with preoperative LFPTA 42.4 ± 16.4 dB and threshold shift to 83.9 ± 27.8 dB. Among the 9 patients where RT-ECochG was used, 8 (88.9%) had low-frequency HP postoperatively with preoperative LFPTA 46.5 ± 16.0 dB and threshold shift to 62.6 ± 19.0 dB. Difference between threshold shift postoperatively with and without RT-ECochG was significant (P = .002, Mann-Whitney U test). Conclusion: RT-ECochG-guided insertion may be required for consistent HP outcomes following CI624 implantation. This may allow the surgeon to decide the depth of electrode insertion in the effort to preserve low-frequency hearing. Further investigation is needed to evaluate whether long-term HP can be maintained using CI624.