Abstract
The use of respiration-correlated cone-beam computed tomography (hereafter, referred to as four-dimensional cone-beam CT; 4D CBCT) appears to be crucial for implementing precise radiation therapy for lung cancer patients. With the 4D CBCT mounted on linear accelerator (LINAC), the mean position, trajectory, and shape of a moving tumor can be verified just prior to treatment. This reconstruction technique is also applicable for in-treatment imaging by accompanying a rotational treatment such as a volumetric modulated arc therapy (VMAT). In this chapter, we introduce the principle of 4D CBCT reconstruction and the planning strategy of the stereotactic body radiation therapy (SBRT) for lung cancer patients with VMAT. Combining 4D CBCT with VMAT delivery, we establish the novel clinical verification by use of in-treatment 4D CBCT.
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