Abstract
IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) continues to have a devastating impact across the globe. However, little is known about the disease course in...
Highlights
In March 2020 the government introduced the concept of shielding with a new description of ‘clinically extremely vulnerable’ (CEV) individuals
Little is known about the disease course in patients with autoimmune hepatitis (AIH)
Data for patients with AIH and SARS-CoV-2 infection were combined from three international reporting registries; COVID-Hep, SECURE-cirrhosis and R-LIVER
Summary
In March 2020 the government introduced the concept of shielding with a new description of ‘clinically extremely vulnerable’ (CEV) individuals. Methods Data for patients with AIH and SARS-CoV-2 infection were combined from three international reporting registries; COVID-Hep, SECURE-cirrhosis and R-LIVER. Results Between 25th March and 24th October 2020, data were collected for 932 patients with CLD and SARS-CoV-2 infection including 70 with autoimmune hepatitis (AIH). Alcoholrelated high impact users are a subgroup who have multiple hospital admissions or attendances related to alcohol during a short time-period. A comprehensive individualised care plan, drawing on several sources (acute hospital, community and addicitions services) was agreed for each. This included details of keyworker contact details, a defined management plan, including threshold for admission, along with recommendations for involvement of safeguarding or statutory services, as apporpriate. Large observational multicentre studies underscore continued equipoise regarding the value of pTIPS and, with the inclusion of a recent randomised control trial (RCT), highlight the difficulty in accessing timely interventional radiology to provide a non-emergency service in real-world clinical practice
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