Abstract

Friedman and Rosenman are highlighting behavioral type A as a major riskfactor for evolution worsening of myocardial infarction, was first and decisive step for clearly specifying the role of supportive psychosocial factors in etiopathogenesis of the coronary heart disease. Then, the reason that this type of behavior has been highlighted in other psychosomatic diseases (and even some healthy subjects) led to the need to fi nd other psychological variables – of personality, especially – associated with type A and convincing predictive value numerous epidemiological and experimental studies. In the last two decades has been it’s presence in some carriers of type A – which showed clinical and laboratory manifestations of coronary artery disease (including exploration angiographic coronary flow and computerized measurements) – this constant in varying degrees of complex traits emotional underpinning of increased aggression: hostility (cognitive and/or behavioral) – in particular internalized anger (anger-in) and ruminative anger. These variables have the correspondent psychological, somatic plan, vascular hyperreactivity to stress hormones (catecholamines and cortisol in particular) resulting in increased plasma cholesterol, myocardial oxygen consumption, the platelets aggregation etc. In essentially agressive featuters frequently expressed to the many distress “collected” by holders type A, pressed myocardium with pathophysiological changes specific for aggression.

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