Abstract
Osteosclerosis in adults with primary hyperparathyroidism is rare; the usual skeletal manifestation, when present, is diffuse osteopenia. We describe a patient with generalized Osteosclerosis in association with primary hyperparathyroidism. The findings are documented by conventional and fine-detail radiography, absorptiometric bone mineral analysis, quantitative microradiography and histologic examination of bone. The unique features are contrasted with the manifestations recorded in a recently studied group of 87 hyperparathyroid patients. The data presented here support a causal relationship in this patient between parathyroid hormone excess and the development of densely sclerotic bones.
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