Abstract
Context: Osteoporosis is a public health problem in India with high incidence of fractures. Aim: The aim of the study w to know the profile of bone parameters and its factors associated with hip fractures in osteoporotic men and women living in low socioeconomic conditions. Settings and Design: A hospital-based case-control study was carried out in Orthopedics ward of the Osmania General Hospital (OGH), Hyderabad, Andhra Pradesh, India. Materials and Methods: A total of 72 men and 72 women aged 35-70 years admitted in OGH with hip fractures during April 2005 to March 2008 were recruited. Age, gender and socioeconomic background matched controls (men: 72 and women: 46) living in Hyderabad were employed. Clinical examination, bone mineral density (BMD), anthropometric measurements, and biochemical markers of bone metabolism were analyzed. Statistical Analysis Used: Descriptive and inferential statistics were carried using SPSS. Results: The mean age of men with fractures was 59.1 ± 9.42 years while, in women, it was 63.6 ± 9.97 years. BMD at the hip (P Conclusion: The high prevalence of Osteoporotic fracture rates in Indians at an early age compared to developed countries highlights the need for dietary diversification, physical activity, self-care management, among the low-income group population to reduce the risk of osteoporosis and its associated risk factors.
Highlights
Osteoporosis is a major public health problem due to its devastating health outcomes and a high incidence of fractures.[1]
The high prevalence of Osteopenia combined with high fracture rates in Indians at an early age compared to developed countries should alert public health professionals and need for tackling the disease at an early stage
Our study demonstrated that low serum calcium levels, and 25-hydroxyl Vitamin D in both genders are associated with lower bone mineral density (BMD) and fractures
Summary
Osteoporosis is a major public health problem due to its devastating health outcomes and a high incidence of fractures.[1]. 20%[5] were hip fractures and these were serious because of their postfracture mortality of 8-33%.[6] Osteoporotic hip fractures occur due to minimal trauma[7] and are strongly related to the low bone mineral density (BMD). BMD is the main determinant of bone fragility leading to hip fractures.[8] Hip BMD was more strongly correlated with hip fractures than the lumbar spine or peripheral BMD measurements.[9]
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