Osteoporosis Presence Verification Using MACE Filter Based Statistical Models of Appearance with Application to Cervical X-ray Images

Abstract

vertebral fracture is a very common outcome of osteoporosis, which is one of the major public health concerns in the world. Early detection of vertebral fractures is important because timely pharmacologic intervention can reduce the risk of subsequent additional fractures. Our goal seeks to develop a computerized method for detection of vertebral fractures by measuring the shape and appearance of vertebrae on cervical xray radiographs in order to assist radiologist’s image interpretation and thus allow the early diagnosis of osteoporosis. The statistical models of shape and appearance are powerful tools for interpreting medical images. This work introduces the application of correlation filter classifiers for identification and verification of the osteoporosis presence in cervical vertebrae training/ testing set. Correlation filter classifiers have been previously applied to other biometric classification tasks, but not to classification of cervical vertebrae images. We describe how the extraction of an appropriate region of interest in the cervical vertebrae surface can be used to design correlation filters that accomplish 90 % recognition on a database of 50 cervical bone shapes.Keywordsx-ray radiographsSegmentationASM modelingCorrelation filtervertebral deformityOsteoporosis