Abstract
Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fractures. Bone mineral density measurements form the basis for an operational definition of osteoporosis with better clinical utility. A study group of the World Health Organization (WHO) has proposed diagnostic guidelines for the interpretation of bone mass measurement in Caucasian women [1]: 1) Severe osteoporosis Bone mineral density (BMD) more than 2.5 standard deviations (SD) below the mean value of the peak bone mass in young normal women and the presence of fractures. 2) Osteoporosis BMD more than 2.5 SD below the mean value of peak bone mass in normal young women. 3) Low bone mass (or osteopenia) BMD within -1 SD and -2.5 SD of the mean value of the peak bone mass in young normal women. 4) Normal BMD not more than 1 SD below the mean value of peak bone mass in young normal women.
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