Osteopoikilosis - associated with dwarfism and presenting as painful joint effusion

Abstract

Osteopoikilosis is usually asymptomatic with only 15-20% patient having pain or joint effusion. Sclerotic dysplasia has multiple differential diagnosis including benign and malignant etiology. Characteristic features of symmetric, round to oval sclerotic lesions in multiple joints with axial skeleton sparing, no cortical erosion, normal clinical and blood investigations help differentiate osteopikilosis from critical malignant sclerotic pathology.