Abstract
Occurrence of Staphylococcus aureus in children with osteomyelitis. This study was conducted at K. M. M. C. & Hospital, Mathura (UP). A total of 60 patients with osteomyelitis contributed to this study from October 2017 to October 2019. Patients with known immunodeficiency syndromes were excluded. Specimen collections were meticulously performed to avoid contamination which was accomplished by needle aspiration or surgical sampling. Staphylococcus aureus was recovered in more than half of the cases of osteomyelitis in both infants and children. Amikacin, Clindamycin and Cefazolin were effective in such cases. The distal end of the femur and upper-end tibia were the most common sites of infection where boys were more infected than girls. The haematogenous route was the main cause of the transmission of osteomyelitis in children. Principally Staphylococcus aureus causes the majority of cases of osteomyelitis in children followed by H. influenza, Group B Streptococcus, P. aeruginosa, E. coli and Serratia marcescens.
Highlights
Osteomyelitis is an inflammation in bone which is caused by various bacteria[1]
Infections caused by methicillin resistant Staphylococcus aureus (MRSA) are very common globally which is responsible for causing invasive infections in children which may lead to higher morbidity and mortality[4,5,6]
Out of 60 patients, most common organism involved in osteomyelitis is Staphylococcus aureus in forty eight patients (80%) including MRSA in 4 patients
Summary
Osteomyelitis is an inflammation in bone which is caused by various bacteria[1]. Haematogenous is the main route of causing osteomyelitis in children whereas non-haematogenous route is not common[3]. Staphylococcus aureus is one of the main causes of osteomyelitis, accounting approximately 70–90% cases. Infections caused by methicillin resistant Staphylococcus aureus (MRSA) are very common globally which is responsible for causing invasive infections in children which may lead to higher morbidity and mortality[4,5,6]. Hematogenous-osteomyelitis begins with bacterial deposition in the metaphysis because of stasis of blood in hair pin like arrangement of blood vessels, deficiency of reticuloendothelial cells at metaphysis, high vascularity at metaphysic and predisposition to trauma[8]. This study was conducted to find out the incidence of osteomyelitis so that better clinical management could be provided to children
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