Abstract

A 64-year-old man was referred with upper abdominal pain of 6-months duration. He reported no weight loss, fever or night sweats. Clinical chemistry revealed cholestasis. A biliary stent had previously been inserted at the referring hospital due to bile duct obstruction. EGD, using a side viewing duodenoscope, showed a red fleshy tumour protruding through the papillary orifice (Fig. 1). The biopsy specimen revealed highly atypical, ovoid to spinde-shaped, mononuclear cells. These were admixed with histiocytes that did not show cytologic atypia, and with large multinuclear osteoclast-like giant-cells (Fig.

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