Abstract
Ossifying fibroma is a well-delineated lesion, composed by fibrous tissue and mineralized matrix of odontogenic or periodontal origin. It is commonly found in the posterior mandible of women between their 20th and 40th years. It is asymptomatic but detectable by routine radiographs. Standard care involves resection followed by bone graft, with good prognosis and unlikely recurrence or malignant transformation. This study reports a case (female patient, 40 years old) presenting with a radiolucent lesion with internal calcification between the teeth 34 and 43. Clinical and imaging findings also included expansion of the symphysis with collapsing cortical bone and root dislodgement. Biopsy revealed fibrous tissue with mineralized areas resembling immature trabecular bone or cementum, leading to the diagnosis of central ossifying fibroma. Treatment involved block resection and bone grafting. This report highlights the importance of observing clinical, radiographic, and histopathologic changes, as well as follow-up, which extend for 9 years in this case, without recurrence.
Published Version
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