Abstract
1. 1. Previously it has been shown that the nitrogenous compounds in the cells of Melanopsis trifasciata (especially the amino acids) increase or decrease in concentration with a rise or fall in salinity but by a much greater extent than is expected by dilution effects. 2. 2. Puromycin and radioactive alanine were used to see what controlled the possible balance between amino acids and proteins in response to osmotic changes. 3. 3. The system was simulated on isolated tissue preparations from the foot muscle as for the whole animal. 4. 4. The time relationship between the change in total fresh weight, the sodium ion concentration and the amino nitrogen concentration was recorded. 5. 5. A possible mechanism of control was put forward.
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