Abstract

Introduction: creatine and caffeine are among the most widely used substances as ergogenic resources bythose looking to increase muscle mass, reduce body fat, and improve athletic performance. However, littleis known about the possible synergistic effects of concomitant use of these substances. Objective: to searchfor evidence in the scientific literature about the possible effects of administration of these substances insubjects undergoing physical exercise. Method: a search in LILACS, SciELO, and PubMed databases,using the terms “creatine”, “caffeine”, “resistance exercise”, and “dietary supplementation”. Results: elevenarticles were selected for analysis of the results, as they fulfilled the inclusion criteria. Of these, only fivedealt with exclusive use of creatine associated with caffeine, and the remaining with other substancesmarketed as dietary supplements. The few studies on the concomitant use of creatine with caffeine differgreatly in the testing and supplementation protocols applied, making it difficult to conclude if the use ofsuch substances can actually be beneficial to consumers. Conclusion: the results of three articles evidencedan annulment effect of caffeine on the ergogenic effects of creatine, and the others presented conflictingevidence on the variables analyzed.

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