Abstract
thorax. 1,2 They concluded that this orthostatic tachycardia syndrome seemed similar to “effort syndrome, irritable heart, or neurocirculatory asthenia” the synonyms of the day for what we now call CFS. McLean and Allen reported that patients improved by increasing their intake of fluids and sodium, and by sleeping with the head of the bed elevated. The head-up bed may have helped to conserve intravascular volume by reducing blood flow to the kidney at night. It is a medical curiosity that these detailed observations were largely ignored for several decades. In this issue of The Journal, 3 articles address related aspects of orthostatic control of blood pressure and heart rate, 3-5 two of which take advantage of newer methodologic tools to better understand microvascular flow and
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