Abstract

This study aimed to explore the effect of orthokeratology (Ortho-K) combined with visual motor training in juvenile myopia. We included 156 myopia patients, which were randomly divided into the combined (visual motor training+Ortho-K) and Ortho-K (only) groups. Corneal morphological changes (horizontal keratometry [HK], vertical keratometry [VK], central corneal thickness [CCT], and corneal endothelial cell density), regulatory function (positive and negative relative accommodation [PRA, NRA], regulatory amplitude, and regulatory sensitivity), ocular axis, visual acuity (naked visual acuity, Diopter), tear film stability (BUT test and SIT test), intraocular pressure, and safety before and after treatment were compared between groups. Moreover, we performed a Spearman correlation analysis on the effects of initial age and diopter on axial growth. After treatment, HK, VK of cornea, and CCT levels significantly decreased in both groups while no significant changes were found in endothelial cell density. In the combined group, there was a higher improvement in PRA, accommodation amplitude, and accommodation sensitivity, which could delay ocular axis growth and improve naked eye vision and diopters. Meanwhile, a significant negative correlation was found between patients’ initial age and axial growth. Moreover, BUT and SIT recovery in the combined group were relatively better after wearing Ortho-K. In conclusion, Ortho-K combined with visual motor training could better correct the vision of juvenile myopia patients and delay ocular axis growth. In addition, the earlier the intervention, the better the effect.

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