Abstract
Background: Melanotic neuroectodermal tumor of infancy (MNTI) is a very rare tumor, and case reports of orthodontic treatment for patients with MNTI may be previously unreported. This article describes the orthodontic treatment for a 7-year-old girl with MNTI in the mandible. Case: Her chief complaint was anterior crossbite. Although she had an MNTI diagnosis at the age of 8 months, it remained subclinical. Therefore, she has been regularly followed-up by computed tomography (CT) and magnetic resonance (MR) imaging without aggressive treatment. We had worried about the stimulation of MNTI on the mandible by changing her occlusal position with orthodontic treatment. Therefore, we sufficiently explained to her and her family that orthodontic treatment was at risk for worsening MNTI. However, they desired treatment that consisted of maxillary protraction and slow expansion to correct anterior crossbite and encourage the permanent tooth eruption. After 19 months of active orthodontic treatment, the anterior crossbite was improved, and the eruption of permanent teeth made good progress. No evidence of progression and exacerbation of MNTI has been found by both CT and MR imaging. As the observation period is still short, we need a careful and long-term follow-up of her occlusion and MNTI. Furthermore, when we encounter rare cases without previous experience and reports, informed consent was of particular importance.
Highlights
Anterior crossbite is defined as a condition characterized by the anterior negative overjet [1]
While the observation period is still short, we present early treatment anterior crossbite for the child patient her occlusion is wellthe maintained and sheofdoes not have deteriorating findings of with
As for Melanotic neuroectodermal tumor of infancy (MNTI), both computed tomography (CT) and magnetic resonance imaging (MRI) found no evidence of progression and exacerbation until now
Summary
Anterior crossbite is defined as a condition characterized by the anterior negative overjet [1]. MNTI is generally considered a benign tumor in newborns, it has a possibility of becoming malignant and metastatic [13,14] This tumor often tends to be characterized by rapid growth and aggressive bone destruction without pain and exulceration [12]. Sci. 2021, 11, 11541 malignant and metastatic [13,14] The of other female patients showed treatment for MNTI is surgical resection, but many studies indicate high recurrence rates is a higher prevalence at 3 years of age and older [17]. While the observation period is still short, we present early treatment anterior crossbite for the child patient her occlusion is wellthe maintained and sheofdoes not have deteriorating findings of with.
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