Abstract
We performed a serologic investigation to determine whether orthobunyaviruses commonly infect humans in the Yucatan Peninsula of Mexico. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization test in 146 (18%) of 823 persons tested. Further studies are needed to determine health risks for humans from this potentially deadly group of viruses.
Highlights
A subset of serum samples with antibodies that neutralized Cache Valley virus (CVV) were titrated and further analyzed by plaque reduction neutralization test (PRNT) by using CVV, Cholul virus (CHLV) (strain CHLV-Mex07), Kairi virus (KRIV) (strain KRIV-Mex07), South River virus (SOURV) (strain NJO-94f), Maguari virus (strain BeAr7272), and Wyeomyia virus (strain prototype)
We performed a serologic investigation to determine whether orthobunyaviruses commonly infect humans in the Yucatan Peninsula of Mexico
Another explanation is that some of these persons had been infected with an orthobunyavirus not included in the plaque reduction neutralization test (PRNT), all orthobunyaviruses known to occur in the Yucatan Peninsula were represented
Summary
A subset of serum samples with antibodies that neutralized CVV were titrated and further analyzed by PRNT by using CVV, CHLV (strain CHLV-Mex07), KRIV (strain KRIV-Mex07), SOURV (strain NJO-94f), Maguari virus (strain BeAr7272), and Wyeomyia virus (strain prototype). Antibodies that neutralized CVV were detected in 146 (18%) of 823 study participants.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
