Abstract

A 64-year-old male patient presented with a complaint of a painful lesion in the mouth lasting 2 months, and he had lost 10 kg during this time. The patient reported previous treatment attempts with amoxicillin/clavulanic acid and clindamycin with no response and a medical history of diabetes. On clinical examination, a tumor mass about 6 cm in diameter was observed in the oropharynx, and the dorsum of the tongue was atrophic. Laboratory tests showed anemia, lymphopenia, anisocytosis, erythrocyte sedimentation rate of 120 mm/h, fasting blood glucose of 140 mg/dL, and a negative HIV test. An incisional biopsy was performed, where hematoxylin/eosin (H&E) examination was compatible with lymphoma, and immunohistochemical analysis confirmed the diagnosis of diffuse large B-cell lymphoma. The patient was referred to the oncology service and started chemotherapy (R-CHOP) but then developed septic shock, was sent to the intensive care unit, and died a month later.

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