Abstract
To investigate orofacial traits and general factors related to oral health-related quality of life in acromegaly patients. A cross-sectional study with 34 acromegaly patients was conducted. The OHIP-14 questionnaire was used to assess oral health-related quality of life scores. To assess orofacial and occlusion morphology, an oral evaluation was performed. Correlation measures, multiple linear regression and a structural equation model (SEM) were used in the statistical analysis. The presence of arthrosis (SC=0.467, SE=0.155, p=0.003) and smoking history (SC=0.459, SE=0.206, p=0.026) were associated with a negative impact on oral health-related quality of life. Mandibular protrusion was related to physical pain (β=2.74, p=0.029). Anterior open bite (β=4.44, p=0.004) and anterior crossbite (β=2.61, p=0.026) were related to psychological disability. Diastema was related to social disability (β=3.42, p=0.037) and handicap (β=2.74, p=0.044). The findings suggest that smoking, arthrosis and orofacial alterations (mandibular protrusion, open bite, crossbite and diastema) have a negative impact on oral health-related quality of life in acromegaly patients.
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