Abstract

The importance of LDL cholesterol in atherosclerotic cardiovascular disease (ASCVD) is highlighted by countless studies establishing its role in disease causality and clinical trials showing a direct association between lowering LDL cholesterol and reductions in cardiovascular risk. Although treatment guidelines have increasingly emphasised the importance of lipid lowering in cardiovascular prevention, many people with dyslipidemia do not achieve optimal management. Clinical registries consistently show that many people deemed to be at high cardiovascular risk are treated with low intensity lipid-lowering therapy but more than 50% do not achieve guideline mandated LDL cholesterol treatment goals.

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