Abstract
Assessment of the thyroid-pituitary axis was performed in uncontrolled (20 cases) and controlled (22 cases) insulin-dependent young diabetics who were university students attending the university hospital. A third age-matching group (21 normal subjects) was also investigated. Fasting plasma glucose level as well as 2 hours after an oral glucose meal (50 g) were determined. Thyroxine (T4), triiodothyronine (T3) and thyroid stimulaling hormone (TSH) were assayed by RIA. The data obtained showed a lowered level of T3 and T4and a raised level in TSH level in uncontrolled young diabetics than the corresponding values for age matching normals. The group of controlled diabetics showed near normal T3 level and increased T4 but still lower than normal. TSH levels dropped significantly to the normal level.
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