Origin of rare bovine rotavirus strains detected from Japanese children

Kei Numazaki

doi:10.15761/pd.1000164

Abstract

Origin of rare bovine rotavirus strains detected from Japanese children

Highlights

Full-genome sequences of RV strains have been increasingly analyzed in order to understand the interspecies transmission, reassortment, and evolutionary relationships between human and animal RVs
In the previous study [15,16], nearly full-length sequences of all the gene segments were determined to investigate the genetic origin of the unique human G6P[9] RVs detected in Japan
All other genes of the detected strain except for the NSP3 were relatively closely related to at least one of the human G6 RVs reported in Europe and the U.S In a study from Miyagi Prefecture of Japan G6P [9] (M72S11) per sample was found from a 2-year-old toddler in 2011 [29]

Summary

Introduction

Full-genome sequences of RV strains have been increasingly analyzed in order to understand the interspecies transmission, reassortment, and evolutionary relationships between human and animal RVs. In the previous study [15,16], nearly full-length sequences of all the gene segments were determined to investigate the genetic origin of the unique human G6P[9] RVs detected in Japan. The authors [21] considered that their isolates represented reassortment events between bovine-like human rotaviruses and human/feline AU1-like rotaviruses. The patient from whom the unique human G6P[9] RVs detected recently in Japan did not have previous contact with obvious bovine or other sources of infection.

Results

Conclusion