Abstract
We report on the fabrication of oriented collagen films by drying a dilute collagen solution on a polydimethylsiloxane (PDMS) substrate with a micrometer grooved surface.
Highlights
We report on the fabrication of oriented collagen films by drying a dilute collagen solution on a polydimethylsiloxane (PDMS) substrate with a micrometer grooved surface
We successfully observed that the fabricated collagen film exhibited optical and mechanical anisotropy depending on the orientation direction
Collagen films were fabricated by drying the dilute collagen solution in a handmade glass box in which a PDMS substrate was adhered at the bottom
Summary
We report on the fabrication of oriented collagen films by drying a dilute collagen solution on a polydimethylsiloxane (PDMS) substrate with a micrometer grooved surface. The resultant films show optical and mechanical anisotropy along the groove direction, and have a high mechanical strength with Young’s modulus of 2.3 GPa. This process might enable collagen materials to be applied to anisotropic biocompatible substrates, large-area functional scaffolds, and soft robotic materials.
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