Orientation dependence of progressive post-yield behavior of human cortical bone in compression

Abstract

Identifying the underlying mechanisms of energy dissipation during post-yield deformation of bone is critical in understanding bone fragility fractures. However, the orientation-dependence of post-yield properties of bone is still poorly understood. Thus, the objective of this study was to determine the effect of loading direction on the evolution of post-yield behavior of bone using a progressive loading protocol. To do so, cylindrical compressive bone samples were prepared each in the longitudinal, circumferential and radial directions, from the mid-shaft of cadaveric femurs procured from eight middle-aged male donors (51.5±3.3 years old). These specimens were tested in compression in a progressive loading scheme. The results exhibited that the elastic modulus, yield stress, and energy dissipation were significantly greater in the longitudinal direction than in the transverse (circumferential and radial) directions. However, no significant differences were observed in the yield strain as well as in the successive plastic strain with respect to the increasing applied strain among the three orientations. These results suggest that the initiation and progression of plastic strain are independent of loading orientations, thus implying that the underlying mechanism of plastic behavior of bone in compression is similar in all the orientations.