Abstract
Condensation of 5-(hydroxymethyl)furan-2-carboxaldehyde with 4-toluidine yielded a Schiff base (5-((p-tolylimino)methyl)furan-2-ol). A series of seven novel hexa-coordinated organyltellurium(IV) complexes of type TeCl4·HMeFPT, RTeCl3·HMeFPT and R2TeCl2·HMeFPT (where R belongs to 4-methoxyphenyl, 4-hydroxyphenyl and 3-methyl-4-hydroxyphenyl; L belongs to HMeFPT i.e. Schiff base have been prepared and characterized by molar conductance, IR, UV, 1H NMR, 13C NMR, mass spectroscopy and elemental analysis. Thus according to spectroscopic studies, Schiff base ligand functions as a NO donor bidentate ligand across all organyltellurium(IV) complexes via the azomethine nitrogen atom and the oxygen atom of the furan ring. The above mentioned spectroscopic analysis indicated that all the organyltellurium(IV) complexes have distorted octahedral geometry. Schiff base and all the organyltellurium(IV) complexes had their geometry optimized and theoretical quantum mechanical characteristics computed. The octahedral geometry for complexes is also suggested by this computing analysis. The antimicrobial property of the Schiff base ligand and its organyltellurium(IV) complexes was evaluated in vitro against different bacterial strains viz. A. clavatus, C. albicans, A. niger, S. pyogenes, S. aureus, E. coli and P. aerugenosa. Antimicrobial property of heterocyclic bidentate Schiff base and its organyltellurium(IV) complexes was found to be significantly greater than that of some standard antibiotics.
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