Organophotocatalyzed Synthesis of Vinyl‐SCF3 and Benzoyl‐SCF3 Using a New N‐(SCF3)(CF3)‐Shelf‐Stable Reagent

Abstract

AbstractWe report the photocatalyzed C−SCF3 bond formation using a new shelf‐stable PhPh‐N‐(SCF3)(CF3) reagent I in combination with 4CzIPN as organophotocatalyst under blue LED irradiation. While the synthesis of vinyl‐SCF3 is performed in the presence of bromide salts as an activator of reagent I, the synthesis of trifluoromethylthioesters was undertaken using aldehydes as starting material in the presence of a hydrogen atom transfer catalyst (HAT). Preliminary mechanistic investigations including EPR spectroscopy and cyclic voltammetry analysis shed the light on the reaction mechanisms.