Abstract

In a Policy Forum, Irva Hertz-Picciotto and colleagues review the scientific evidence linking organophosphate pesticides to cognitive, behavioral, and neurological deficits in children and recommend actions to reduce exposures.

Highlights

  • Governments phase out chlorpyrifos and other OP pesticides, monitor watersheds and other sources of human exposures, promote use of integrated pest management (IPM) through incentives and training in agroecology, and implement mandatory surveillance of pesticide-related illness

  • Agricultural entities accelerate the development of nontoxic approaches to pest control through IPM and ensure the safety of workers through training and provision of protective equipment when toxic chemicals are to be used

  • Organophosphate (OP) compounds were originally developed as human nerve gas agents during the 1930s–1940s, and some were later adapted as insecticides at lower doses [1]

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Summary

Summary points

Widespread use of organophosphate (OP) pesticides to control insects has resulted in ubiquitous human exposures. High exposures to OP pesticides are responsible for poisonings and deaths, in developing countries. Governments phase out chlorpyrifos and other OP pesticides, monitor watersheds and other sources of human exposures, promote use of integrated pest management (IPM) through incentives and training in agroecology, and implement mandatory surveillance of pesticide-related illness. Health professions implement curricula on the hazards from OP pesticides in nursing and medical schools and in continuing medical education courses and educate their patients and the public about these hazards. Agricultural entities accelerate the development of nontoxic approaches to pest control through IPM and ensure the safety of workers through training and provision of protective equipment when toxic chemicals are to be used. IHP submitted information to the US EPA regarding regulation of chlorpyrifos in agriculture (unpaid)

Introduction
Findings
42 Sulfotepp

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